The metallogenic characteristics, tectonic setting, and structure of F.Y.R.O. Macedonian territory, Kozuf-Aridea and Kadica-Bucovic ore districts and its specific formation features are discussed in this paper on the basis of new results and data obtained by previous investigations. The interpretation of satellite images and morphostructural analyses were employed successfully for revealing the ore-concentrating structural features. The tectonic elements of the present-day topography were marked out and compared with the structural features that existed during the period of ore formation. The use of the present-day structural landforms of F.Y.R.O. Macedonia for reconstruction of the tectonic elements of ore-bearing periods became possible after substantiating their inherited evolution. The ring structure occupies a special position in southern F.Y.R.O. Macedonia and ore districts are controlled. Geological, geochemical, and morphostructural attributes allow interpretation of this structure as a center of long-term endogenous activity that evolved since the Jurassic-Cretaceous time.